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SOS1-IN-12

SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1].

Product Specifications

CAS Number

2654741-56-5

UNSPSC

12352005

Target

Ras; SOS1

Type

Reference compound

Related Pathways

GPCR/G Protein; MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sos1-in-12.html

Solubility

10 mM in DMSO

Smiles

CC1=NN=C(C2=CC(N3CCNCC3)=CC=C21)N[C@@H](C4=CC=CC(C(F)(F)F)=C4C)C

Molecular Formula

C23H26F3N5

Molecular Weight

429.48

References & Citations

[1]Matthew Arnold Marx, et al. Sos1 inhibitors. WO2021127429A1 (compound 6-4)

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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