BMS-604992 (dihydrochloride)
BMS-604992 (EX-1314) dihydrochloride is a selective, orally active small-molecule growth hormone secretagogue receptor (GHSR) agonist. BMS-604992 dihydrochloride demonstrates high-affinity binding (ki=2.3 nM) and potent functional activity (EC50=0.4 nM) . BMS-604992 dihydrochloride can stimulate food intake in rodents[1].
Product Specifications
CAS Number
1469750-46-6
Product Name Alternative
EX-1314 (dihydrochloride)
UNSPSC
12352005
Target
GHSR
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bms-604992-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC2=NN=C([C@H](NC(C(C)(N)C)=O)COCC3=CC=CC=C3)N12)N(CC(N)=O)C.[H]Cl.[H]Cl
Molecular Formula
C24H33Cl2N7O5
Molecular Weight
570.47
References & Citations
[1]Charoenthongtrakul S, et al. Enhanced gastrointestinal motility with orally active ghrelin receptor agonists. J Pharmacol Exp Ther. 2009;329 (3) :1178-1186.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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