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Monoamine oxidase/Aromatase-IN-1

Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a highly potent monoamine oxidase (MAO) and aromatase dual inhibitor with IC50s of 39 nM and 31 nM for MAO-B and aromatase, respectively. Monoamine oxidase/Aromatase-IN-1 can be used for researching neurological disorder and breast cancer[1].

Product Specifications

UNSPSC

12352005

Target

Cytochrome P450; Monoamine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/monoamine-oxidase-aromatase-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC)CC1=CSC(N/N=C/C2=CC=C3C=C(OC)C=CC3=C2)=N1

Molecular Formula

C19H19N3O3S

Molecular Weight

369.44

References & Citations

[1]Evren AE, et al. Synthesis of novel thiazolyl hydrazone derivatives as potent dual monoamine oxidase-aromatase inhibitors. Eur J Med Chem. 2022;229:114097.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Aromatase/CYP19A1; MAO-B

Frequently Asked Questions

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