Anti-MRSA agent 3
Anti-MRSA agent 3 (compound 18) has highly inhibitory activity against Methicillin-resistant Staphylococcus aureus (MRSA) with MIC of 0.098 μg/ml, and low cytotoxicity in normal cells. Anti-MRSA agent 3 has relatively strong ability to destroy bacterial cell wall and membrane, high binding affinity to bacterial genomic DNA[1].
Product Specifications
CAS Number
2416909-42-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/anti-mrsa-agent-3.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C3NC4=C(C=C(C(NC5=C6C=CC=CC6=CC=C5)=O)C=C4)C3=CC=[N+]2C7=C1C=CC=C7.[Br-]
Molecular Formula
C29H18BrN3O2
Molecular Weight
520.38
References & Citations
[1]Wang X, et al. Fascaplysin derivatives binding to DNA via unique cationic five-ring coplanar backbone showed potent antimicrobial/antibiofilm activity against MRSA in vitro and in vivo. Eur J Med Chem. 2022;230:114099.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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