Anticancer agent 40
Anticancer agent 40 (compound 3e) is a potent anticancer agent. Anticancer agent 40 shows anticancer activities with IC50s of 0.94, 0.98, 0.96, 0.95, 2.13 nM for SKBR-3, SKOV-3, PC-3, U-87, HDF cells, respectively[1].
Product Specifications
CAS Number
2760658-33-9
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-40.html
Solubility
10 mM in DMSO
Smiles
CC(N[C@H]1CCC2=CC(OC)=C(OC)C(OC)=C2C3=C1C=C(OC/C=C/C)C(C=C3)=O)=O
Molecular Formula
C25H29NO6
Molecular Weight
439.50
References & Citations
[1]Pyta K, et al. Regioselective approach to colchiceine tropolone ring functionalization at C (9) and C (10) yielding new anticancer hybrid derivatives containing heterocyclic structural motifs. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :597-605.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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