Carbonic anhydrase inhibitor 9
Carbonic anhydrase inhibitor 9 is a potent carbonic anhydrase (CA) inhibitor with Kis of 56.4 and 56.9 nM for hCA II and IX, respectively. Antiproliferative activity[1].
Product Specifications
CAS Number
3033042-50-8
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/carbonic-anhydrase-inhibitor-9.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(Br)C=C1)CN2C(/C(C3=C2C=CC=C3)=N\NC4=CC=C(S(=O)(N)=O)C=C4)=O
Molecular Formula
C22H18BrN5O4S
Molecular Weight
528.38
References & Citations
[1]Said MF, et al. Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity. J Enzyme Inhib Med Chem. 2022;37 (1) :701-717.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA IX
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