SDOX
Product Specifications
UNSPSC Description
SDOX is the Doxorubicin (DOX) proagent. The loaded DOX proagents (SDOX) which can release the parent agents DOX triggered by excessive GSH in tumor cells, minimize the unexpected side effects on normal tissues without compromising the potency[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sdox.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OCCOCCOCCOC(CCC(OCCSSCCOC(N[C@H]4C[C@@H](O[C@H]([C@H]4O)C)O[C@@H]5C6=C(C[C@](O)(C5)C(CO)=O)C(O)=C7C(C(C8=C(OC)C=CC=C8C7=O)=O)=C6O)=O)=O)=O)([H])[C@@]9([H])[C@](CC3)([C@@](CC9)([H])[C@H](C)CCCC(C)C)C
Molecular Weight
1324.63
References & Citations
[1]Yi Zhao, et a l. pH-redox responsive cascade-targeted liposomes to intelligently deliver doxorubicin prodrugs and lonidamine for glioma. Eur J Med Chem. 2022 May 5;235:114281.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144769/SDOX-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144769/
Clinical Information
No Development Reported
CAS Number
2921601-78-5
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