HSR1304
HSR1304 (Compound 5d) is a potent inhibitor of NFκB. The multifunctional transcription factor, nuclear factor-κB (NF-κB), is broadly involved in multiple human diseases, such as cancer and chronic inflammation. HSR1304 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
2763363-08-0
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsr1304.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC=C1NC(C2C3=CC=CC=C3CCN2C(C4=CC=C(C=C4)Cl)=O)=O
Molecular Formula
C24H21ClN2O3
Molecular Weight
420.89
References & Citations
[1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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