NF-κB-IN-3
NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].
Product Specifications
CAS Number
[1873311-82-0]
UNSPSC
12352005
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nf-κb-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCC2=CC=CC=C2N1C(C3=CC=CC(Cl)=C3)=O)NC4=CC=CC=C4C(F)(F)F
Molecular Formula
C24H18ClF3N2O2
Molecular Weight
458.86
References & Citations
[1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NF-κB
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6359380-01 0.1 mL
TSC2, Phosphorylated (S1421) (Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog) (MaxLight 405)
Ask
View Details 
MBS6359380-02 5x 0.1 mL
TSC2, Phosphorylated (S1421) (Tsc2, Tuberin, Tuberous sclerosis 2 protein homolog) (MaxLight 405)
Ask
View Details 