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NF-κB-IN-3

NF-κB-IN-3 (Compound 2) is a NF-κB inhibitor with an IC50 of 0.70 µM. NF-κB-IN-3 can be used as an antitumor agent[1].

Product Specifications

CAS Number

1873311-82-0

UNSPSC

12352005

Target

NF-κB

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nf-κb-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C1CCC2=CC=CC=C2N1C(C3=CC=CC(Cl)=C3)=O)NC4=CC=CC=C4C(F)(F)F

Molecular Formula

C24H18ClF3N2O2

Molecular Weight

458.86

References & Citations

[1]Sim S, et al. Design, synthesis, and biological evaluation of potent 1,2,3,4-tetrahydroisoquinoline derivatives as anticancer agents targeting NF-κB signaling pathway. Bioorg Med Chem. 2021 Sep 15;46:116371.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

NF-κB

Frequently Asked Questions

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