BRG1-IN-1
Product Specifications
UNSPSC Description
BRG1-IN-1 (Compound 11d) is a potent inhibitor of BRG1. BRG1-IN-1 shows better efficacy than PFI-3 in sensitizing GBM cells to the antiproliferative and cell death inducing effects of Temozolomide in vitro. BRG1-IN-1 enhances the inhibitor effect of Temozolomide on the growth of subcutaneous GBM tumors[1].
Type
Reference compound
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brg1-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(/C=C/N1[C@@H]2C[C@H](C1)N(C3=CC=C(F)C=C3)C2)C4=CC=CC=C4
Molecular Weight
322.38
References & Citations
[1]He Y, et al. Novel structural-related analogs of PFI-3 (SRAPs) that target the BRG1 catalytic subunit of the SWI/SNF complex increase the activity of temozolomide in glioblastoma cells. Bioorg Med Chem. 2022 Jan 1;53:116533.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144720/BRG1-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144720/
Clinical Information
No Development Reported
CAS Number
2616813-99-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal UBN1 Antibody (UBN1-02) [Alexa Fluor 488]](https://cdn.genprice.uk/genprice/genprice2.png)
