HIV-1 inhibitor-17
HIV-1 inhibitor-18 (compound V-25i) is a potent HIV-1 capsid inhibitor with an EC50 value of 2.57 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >8.55) [1].
Product Specifications
CAS Number
2764787-76-8
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-17.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC1=CC=CC=C1)C(N(C2=CC=C(OC)C=C2)C)=O)C3=CC=CC(S(=O)(N4CCC5=C4C=CC(N)=C5)=O)=C3
Molecular Formula
C32H32N4O5S
Molecular Weight
584.69
References & Citations
[1]Li J, et al. Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors. Bioorg Med Chem. 2021;48:116414.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
Frequently Asked Questions
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