HIV-1 inhibitor-18
HIV-1 inhibitor-18 (compound II-13c) is a potent HIV-1 capsid inhibitor with an EC50 value of 5.14 μM for HIV-1 NL4-3. HIV-1 inhibitor-18 has certain cytotoxicity (MT-4 cells CC50 >9.51) [1].
Product Specifications
CAS Number
[2764787-56-4]
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-18.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C1=CC=C(OC)C=C1)C)[C@@H](NS(=O)(CC(N(C2=CC=C(OC)C=C2)C)=O)=O)CC3=CC=CC=C3
Molecular Formula
C27H31N3O6S
Molecular Weight
525.62
References & Citations
[1]Li J, et al. Design, synthesis, and antiviral activity of phenylalanine derivatives as HIV-1 capsid inhibitors. Bioorg Med Chem. 2021;48:116414.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HIV-1
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