What is the catalog number for Axl-IN-3?

The catalog number for Axl-IN-3 is HY-144706.

What sizes are available for Axl-IN-3?

Axl-IN-3 is available in the following size(s): 1 Each.

Is Axl-IN-3 in stock?

Axl-IN-3 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Axl-IN-3?

Axl-IN-3 is manufactured by QuantiMol.

What is the estimated delivery time for Axl-IN-3?

Estimated delivery time for Axl-IN-3 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Axl-IN-3?

The safety data sheet for Axl-IN-3 is available here: http://file.medchemexpress.com/batch_PDF/HY-144706/.

Axl-IN-3

Axl-IN-3 is a potent, selective and orally active AXL kinase inhibitor with an IC50 of 41.5 nM. Axl-IN-3 has lower inhibition of other kinases[1].

Product Specifications

CAS Number

2783991-34-2

UNSPSC

12352005

Target

TAM Receptor

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/axl-in-3.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)N2C=C(C=N2)C3=NNC4=C3C=C(C(Cl)=C4)N[C@@H]5CCN(C5)C6COC6

Molecular Formula

C24H25ClN6O2

Molecular Weight

464.95

References & Citations

[1]Pearly Shuyi Ng, et al. Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors. Bioorg Med Chem. 2021 Nov 1;49:116437.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Axl

Frequently Asked Questions

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