ERRα antagonist-2
ERRα antagonist-2 (Compound 11) is a potential ERRα (estrogen related receptor α) inverse agonist with an IC50 of 0.80 μM. ERRα antagonist-2 suppresses the migration and invasion of the ER-negative MDA-MB-231 cell line. ERRα antagonist-2 inhibits breast cancer growth in vivo[1].
Product Specifications
CAS Number
[3032965-02-6]
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/errα-antagonist-2.html
Purity
99.07
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
COC1=CC=C(C=C1)OC2=CC=CC=C2NS(=O)(C3=CC=C([N+]([O-])=O)C=C3)=O
Molecular Formula
C19H16N2O6S
Molecular Weight
400.41
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144699/ERRα-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144699/ERRα-antagonist-2-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERRα
Available Sizes
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