ALDH3A1-IN-2
ALDH3A1-IN-2 (Compound 19) is a potent inhibitor of ALDH3A1 with an IC50 of 1.29 μM. Aldehyde dehydrogenases (ALDHs) are overexpressed in various tumor types including prostate cancer. ALDH3A1-IN-2 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
374635-48-0
UNSPSC
12352005
Target
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aldh3a1-in-2.html
Solubility
10 mM in DMSO
Smiles
O=CC1=CC([N+]([O-])=O)=C(C=C1)N(CC)CC
Molecular Formula
C11H14N2O3
Molecular Weight
222.24
References & Citations
[1]Ibrahim AIM, et al. Expansion of the 4- (Diethylamino) benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65 (5) :3833-3848.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ALDH3
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