MtTMPK-IN-1
Product Specifications
UNSPSC Description
MtTMPK-IN-1 (compound 3) is a potent Mycobacterium tuberculosis thymidylate kinase (MtTMPK) inhibitor with an IC50 value of 2.5 μM. MtTMPK-IN-1 has moderate to weak activity against Mtb H37Rv and low cytotoxicity in human fibroblast cells MRC-5. MtTMPK-IN-1 can be used for researching tuberculosis[1].
Target Antigen
Bacterial; Thymidylate Synthase
Type
Reference compound
Related Pathways
Anti-infection;Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mttmpk-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CN(C(NC1=O)=O)C2CCN(CC2)CC3=NC(OC4=CC=CC=C4)=CC=C3
Molecular Weight
392.45
References & Citations
[1]Song L, et al. Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors. Eur J Med Chem. 2021;225:113784.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144663/MtTMPK-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144663/
Clinical Information
No Development Reported
CAS Number
2799607-58-0
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS520317-01 0.25 mg
Anti-Mouse H-2Db, Affinity Purified (Clone B22-249.R1) (mouse IgG2a)
Ask
View Details MBS520317-02 5x 0.25 mg
Anti-Mouse H-2Db, Affinity Purified (Clone B22-249.R1) (mouse IgG2a)
Ask
View Details 
PC109558-01 100 mg
4-[3-Chloro-5- (trifluoromethyl) -2-pyridyl]piperazine-1-carboxamidine (as HCl salt)
Ask
View Details PC109558-02 250 mg
4-[3-Chloro-5- (trifluoromethyl) -2-pyridyl]piperazine-1-carboxamidine (as HCl salt)
Ask
View Details PC109558-03 500 mg
4-[3-Chloro-5- (trifluoromethyl) -2-pyridyl]piperazine-1-carboxamidine (as HCl salt)
Ask
View Details