AChE-IN-7
AChE-IN-7 (Compound 16) is a selective and potent inhibitor of acetylcholinesterase (eeAChE IC50 = 0.045 μM; eeBuChE IC50 = 19.68 μM) . AChE-IN-7 is safe in vivo and in vitro, and shows good overall pharmacokinetic performance and high bioavailability (F = 55.5%) . AChE-IN-7 also has high BBB permeability[1].
Product Specifications
CAS Number
[2699090-78-1]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C3=NC=CC4=CC(OCCCCN5CCCCC5C)=CC1=C43)C=CC=C2
Molecular Formula
C26H28N2O2
Molecular Weight
400.51
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
More Discoveries
Explore Other Products
Browse additional items from our catalog
482772 100 µL
HLA-A (MHC Class I Antigen, Major Histocompatibility Complex, Class I, A)
Sign In for Pricing
View Details 
