IP2

IP2 is an immunomodulatory agent. IP2 increases PTP (Pioneer Translation Product) -derived antigen presentation in cancer cells. IP2 shows non-cytotoxic for cancer cells. IP2 induces tumor growth defects in mouse[1].

Product Specifications

CAS Number

2247640-44-2

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ip2.html

Solubility

10 mM in DMSO

Smiles

OC1=C2C(C=C(OC2=CC(OP(O[Na])(O[Na])=O)=C1)C3=CC=C(C(C4=C(C5=C(C=C4OP(O[Na])(O[Na])=O)O)OC(C6=CC=C(C=C6)OC)=CC5=O)=C3)OC)=O

Molecular Formula

C32H20Na4O16P2

Molecular Weight

814.40

References & Citations

[1]Letribot B, et al. Biological Investigation of a Water-Soluble Isoginkgetin-Phosphate Analogue, Targeting the Spliceosome with In Vivo Antitumor Activity. J Med Chem. 2022; 65 (6) :4633-4648.