SP inhibitor 1
Product Specifications
UNSPSC Description
SP inhibitor 1 (compound 34) is a selective SARS-CoV-2 spike protein (SP) inhibitor with an IC50 of 3.26 μM, >25 μM, >25 μM for SP, Mpro and PLpro protein, respectively. SP inhibitor 1 is a vitro SARS-CoV-2 replication inhibitor at non-toxic concentrations (0.3250antiviral activity[1].
Target Antigen
SARS-CoV; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sp-inhibitor-1.html
Solubility
10 mM in DMSO
Smiles
COC(C1=CC=C2C(C(CN(CC3=CC=CC=C3)CCC4=CC=C(C=C4)C5=CC=CC=C5)=CN2CC(C)C)=C1)=O
Molecular Weight
530.70
References & Citations
[1]Veronica Di Sarno, et al. Identification of a dual acting SARS-CoV-2 proteases inhibitor through in silico design and step-by-step biological characterization. Eur J Med Chem. 2021 Dec 15;226:113863.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144647/SP-inhibitor-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144647/
Clinical Information
No Development Reported
CAS Number
2766185-81-1
Curated Selection
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