Fmoc-Asn-Pro-Val-PABC-PNP
Fmoc-Asn-Pro-Val-PABC-PNP (compound 6) is a potent ADC Linker[1].
Product Specifications
CAS Number
[2893871-64-0]
UNSPSC
12352005
Target
ADC Linker
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-asn-pro-val-pabc-pnp.html
Purity
99.34
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(OCC1=CC=C(C=C1)NC([C@@H](NC([C@H]2N(CCC2)C([C@@H](NC(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)CC(N)=O)=O)=O)C(C)C)=O)OC6=CC=C(C=C6)[N+]([O-])=O
Molecular Formula
C43H44N6O11
Molecular Weight
820.84
References & Citations
[1]Mohamed Amar IA, et al. Dual intra- and extracellular release of monomethyl auristatin E from a neutrophil elastase-sensitive antibody-drug conjugate. Eur J Med Chem. 2022 Feb 5;229:114063.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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