Neuropeptide Y Y1 receptor antagonist 1
Neuropeptide Y Y1 receptor antagonist 1 (compound 39), a fluorescent probe, is a potent antagonist of neuropeptide Y Y1 receptor (Y1R), with a Ki of 0.19 nM[1].
Product Specifications
CAS Number
[2773476-40-5]
UNSPSC
12171500
Target
Neuropeptide Y Receptor
Type
Dye Reagents
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neuropeptide-y-y1-receptor-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(C(NCCCCOC2=CC=CC([C@@H](C(N[C@H](CCCN/C(N)=N\C(NCCNC(CC)=O)=O)C(NCC3=CC=C(C=C3)O)=O)=O)C4=CC=CC=C4)=C2)=O)=CC=C1C5=C6C=C/C(C=C6OC7=C5C=CC(N(C)C)=C7)=[N+](C)/C)[O-]
Molecular Formula
C62H70N10O10
Molecular Weight
1115.28
References & Citations
[1]Müller C, et, al. Structure-Based Design of High-Affinity Fluorescent Probes for the Neuropeptide Y Y 1 Receptor. J Med Chem. 2022 Mar 24;65 (6) :4832-4853.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Isoform
NPY Y1 receptor
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