SARS-CoV-2 Mpro-IN-1

SARS-CoV-2 Mpro-IN-1 (compound 16b-3) is a potent, selective and irreversible inhibitor of SARS-CoV-2 main protease (Mpro), with an IC50 of 116 nM[1].

Product Specifications

CAS Number

[2758359-91-8]

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-mpro-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(CN1SC2=C(C1=O)C(F)=CC=C2)NC3=CC=CC=C3

Molecular Formula

C15H11FN2O2S

Molecular Weight

302.32

References & Citations

[1]Chen W, et, al. Discovery of highly potent SARS-CoV-2 M pro inhibitors based on benzoisothiazolone scaffold. Bioorg Med Chem Lett. 2022 Feb 15;58:128526.