Xanthine oxidase-IN-5
Product Specifications
UNSPSC Description
Xanthine oxidase-IN-5 is an effective and orally active xanthine oxidase (XO) inhibitor with IC50 value of 0.70 μM. Xanthine oxidase-IN-5 displays favorable agent-like properties with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Xanthine oxidase-IN-5 shows potent hypouricemic effects in hyperuricemic rat model[1].
Target Antigen
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-5.html
Solubility
10 mM in DMSO
Smiles
O=CC1=CC(F)=CC=C1OCC2=CN(CC3=CC=CC(OC)=C3)N=N2
Molecular Weight
341.34
References & Citations
[1]Zhang TJ, Zhang Y, Zhang ZH, et al. Discovery of 4-(phenoxymethyl)-1H-1,2,3-triazole derivatives as novel xanthine oxidase inhibitors. Bioorg Med Chem Lett. 2022;60:128582.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144456/Xanthine-oxidase-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144456/
Clinical Information
No Development Reported
CAS Number
2276711-87-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
