Neuraminidase-IN-5

Neuraminidase-IN-5 (Compound 5b) is a potent inhibitor of neuraminidase with an IC50 of 0.02 μM. Neuraminidase (NA) is a promising target for development of anti-influenza agents. Neuraminidase-IN-5 is a dihydrofurocoumarin derivative compound[1].

Product Specifications

CAS Number

[2473524-63-7]

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/neuraminidase-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(C)C2=CC=C(O/C(C3=O)=C\C4=CC=C(O)C([N+]([O-])=O)=C4)C3=C2O1

Molecular Formula

C19H11NO7

Molecular Weight

365.29

References & Citations

[1] Zhong ZJ, et al. Design, synthesis and biological evaluation of dihydrofurocoumarin derivatives as potent neuraminidase inhibitors. Bioorg Med Chem Lett. 2021;37:127839.