CO delivery molecule 1
CO delivery molecule 1 (compound 4) localizes to the endoplasmic reticulum, mitochondria, and lysosomes. Subcellular localization of CO delivery molecule 1 results in CO-induced toxicity effects. Anti-inflammatory effects of CO delivery molecule 1, as measured by TNF-α suppression, occur at the nanomolar level in the absence of CO release, and are enhanced with visible-light-induced CO release[1].
Product Specifications
CAS Number
1972616-04-8
UNSPSC
12352005
Target
TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/co-delivery-molecule-1.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=CC3=CC=CC=C3C=C2OC(C4=CC=C(N(CC)CC)C=C4)=C1O
Molecular Formula
C23H21NO3
Molecular Weight
359.42
References & Citations
[1]Lazarus LS, et al. Flavonol-Based Carbon Monoxide Delivery Molecule with Endoplasmic Reticulum, Mitochondria, And Lysosome Localization. ACS Med Chem Lett. 2022;13 (2) :236-242. Published 2022 Feb 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
