Antitumor agent-44
Antitumor agent-44 (Compound 5n) disrupts the mitochondrial homeostasis, induces cell cycle arrest and apoptosis in human adenocarcinoma cells. Antitumor agent-44 (Compound 5n) possesses good anti-tumor activity in a lung-cancer-cell xenograft mice model[1].
Product Specifications
CAS Number
[1811548-74-9]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-44.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(OCO2)C2=C1)C3=CC=CC4=C3N(C5=NC=CC=N5)C6=C4C=CC=C6
Molecular Formula
C24H15N3O3
Molecular Weight
393.39
References & Citations
[1]Xiao-Xuan Su, et al. Design, synthesis, and evaluation of 9- (pyrimidin-2-yl) -9H-carbazole derivatives disrupting mitochondrial homeostasis in human lung adenocarcinoma. Eur J Med Chem. 2022 Mar 15;232:114200.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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