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Antitumor agent-43

Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 μM for (T-24 cell) . Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase[1].

Product Specifications

CAS Number

2766035-37-2

UNSPSC

12352005

Target

Apoptosis; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-43.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=NC=CC3=C([N+]([O-])=O)C=CC(C4=C1C=CC=C4)=C23

Molecular Formula

C16H8N2O3

Molecular Weight

276.25

References & Citations

[1]Lan-Shan Liao, et al. One-pot synthesis of oxoaporphines as potent antitumor agents and investigation of their mechanisms of actions. Eur J Med Chem

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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