Antitumor agent-43
Antitumor agent-43 (Compound 4B) is a potent antitumor agent, with an IC50of 0.5 μM for (T-24 cell) . Antitumor agent-43 (Compound 4B) induces cell cycle arrest at G2/M phase[1].
Product Specifications
CAS Number
2766035-37-2
UNSPSC
12352005
Target
Apoptosis; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-43.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC=CC3=C([N+]([O-])=O)C=CC(C4=C1C=CC=C4)=C23
Molecular Formula
C16H8N2O3
Molecular Weight
276.25
References & Citations
[1]Lan-Shan Liao, et al. One-pot synthesis of oxoaporphines as potent antitumor agents and investigation of their mechanisms of actions. Eur J Med Chem
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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