DNA crosslinker 3 (dihydrochloride)
Product Specifications
UNSPSC Description
DNA crosslinker 3 (dihydrochloride) (compound 1) is a potent DNA minor groove binder with DNA binding affinity (ΔTm) of 1.4 °C. DNA crosslinker 3 (dihydrochloride) can be used for researching anticancer[1].
Target Antigen
DNA Alkylator/Crosslinker
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/dna-crosslinker-3-dihydrochloride.html
Solubility
10 mM in DMSO
Smiles
O=C1C=CC(CNC(N)=N)=NN1CC2=CC=C(C=C2)CNC(N)=N.[H]Cl.[H]Cl
Molecular Weight
401.29
References & Citations
[1]Costas-Lago MC, et al. Novel Pyridazin-3(2H)-one-Based Guanidine Derivatives as Potential DNA Minor Groove Binders with Anticancer Activity. ACS Med Chem Lett. 2022;13(3):463-469. Published 2022 Feb 10.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144336/DNA-crosslinker-3-dihydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144336/
Clinical Information
No Development Reported
CAS Number
2761734-21-6
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