CHIKV-IN-3
CHIKV-IN-3 is a potent against two low-passage CHIKV inhibitor with EC50 values of 1.55 and 0.14 μM for CHIKV-122508 and CHIKV-6708, respectively. CHIKV-IN-3 acts on the host cells to interfere with the viral replication. CHIKV-IN-3 displays minimal cytotoxic liability (CC50>100 μM) . Prophylactic effect[1].
Product Specifications
UNSPSC
12352209
Target
CHIKV; DNA/RNA Synthesis
Type
Peptides
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/chikv-in-3.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CCC([C@@H]([C@]1(CCCC2(C)C)C)C/C=C3C(NC4=C/3C=CC=C4Cl)=O)=C
Molecular Formula
C24H30ClNO
Molecular Weight
383.95
References & Citations
[1]Tran QTN, et al. Discovery and development of labdane-oxindole hybrids as small-molecule inhibitors against chikungunya virus infection. Eur J Med Chem. 2022; 230:114110.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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