Aβ-IN-2
Product Specifications
UNSPSC Description
Aβ-IN-2 is a Aβ1–42 aggregation inhibitor. Aβ-IN-2 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-2 can be used for the research of conformational disorders[1].
Target Antigen
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ-in-2.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]1(CCC2C3C=C(C4=CC5=NC6=C(C(C)=C5C[C@@]4(C3CC[C@@]21C)C)C=CC=C6)OCC)[C@@H](CCCC(C)C)C
Molecular Weight
525.81
References & Citations
[1]Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13(3):443-448.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144327/Aβ-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144327/
Clinical Information
No Development Reported
Curated Selection
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