Aβ-IN-2

Aβ-IN-2 is a Aβ1-42 aggregation inhibitor. Aβ-IN-2 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-2 can be used for the research of conformational disorders[1].

Product Specifications

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-in-2.html

Solubility

10 mM in DMSO

Smiles

[H][C@@]1(CCC2C3C=C(C4=CC5=NC6=C(C(C)=C5C[C@@]4(C3CC[C@@]21C)C)C=CC=C6)OCC)[C@@H](CCCC(C)C)C

Molecular Formula

C37H51NO

Molecular Weight

525.81

References & Citations

[1]Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13 (3) :443-448.