Aβ-IN-1

Aβ-IN-1 is a Aβ1-42 aggregation inhibitor. Aβ-IN-1 inhibits Aβ1-42 self-aggregation in vitro by delaying the exponential growth phase or reduces the quantity of fibrils in the steady state. Aβ-IN-1 can be used for the research of conformational disorders[1].

Product Specifications

CAS Number

[2766509-32-2]

UNSPSC

12352005

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/aβ-in-1.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@]3([H])[C@](CC=C1C4=C(C)C5=CC=CC=C5N=C4CC2)([H])[C@@]6([H])[C@](CC3)([C@@](CC6)([H])[C@H](C)CCCC(C)C)C

Molecular Formula

C35H49N

Molecular Weight

483.77

References & Citations

[1]Hélio M T Albuquerque, et al. Steroid-Quinoline Hybrids for Disruption and Reversion of Protein Aggregation Processes. ACS Med Chem Lett. 2022 Feb 14;13 (3) :443-448.