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Galectin-3-IN-2

Galectin-3-IN-2 (Compound 9) is a potent multivalent inhibitor of galectin-3 (Gal-3; IC50=8.3 μM) . Galectin-3 participates in many cancer-related metabolic processes[1]. Galectin-3-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

2883648-71-1

UNSPSC

12352005

Target

Galectin

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/galectin-3-in-2.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@@H]([C@H]([C@@H](O[C@@H]1CO)S[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)OCC3=CN(N=N3)C4=CC=C(C=C4)F)O)O)OCC#C

Molecular Formula

C24H30FN3O10S

Molecular Weight

571.57

References & Citations

[1]David Vrbata, et al. Glycopolymers Decorated with 3- O-Substituted Thiodigalactosides as Potent Multivalent Inhibitors of Galectin-3. J Med Chem. 2022 Mar 10;65 (5) :3866-3878.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Galectin-3

Frequently Asked Questions

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