LY3154885
Product Specifications
UNSPSC Description
LY3154885 is an orally active dopamine D1 receptor positive allosteric modulator (PAM). LY3154885 has an improved agent-agent interactions (DDI) risk profile[1].
Target Antigen
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ly3154885.html
Solubility
10 mM in DMSO
Smiles
CN1N=CC(C2=CC=CC3=C2C[C@H](CO)N(C(CC4=C(Cl)C=CC=C4Cl)=O)[C@H]3C)=C1
Molecular Weight
444.35
References & Citations
[1]Junliang Hao, et al. Synthesis and Preclinical Characterization of LY3154885, a Human Dopamine D1 Receptor Positive Allosteric Modulator with an Improved Nonclinical Drug-Drug Interaction Risk Profile. J Med Chem. 2022 Mar 10;65(5):3786-3797.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144291/LY3154885-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144291/
Clinical Information
Phase 1
CAS Number
2379422-72-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Anti-Lipoprotein Lipase [5D2]: Horseradish peroxidase (HRP)](https://cdn.genprice.uk/genprice/genprice3.png)
MBS375338-01 0.05 mg
Mouse Anti-Lipoprotein Lipase [5D2]: Horseradish peroxidase (HRP)
Ask
View Details ![Mouse Anti-Lipoprotein Lipase [5D2]: Horseradish peroxidase (HRP)](https://cdn.genprice.uk/genprice/genprice2.png)
MBS375338-02 5x 0.05 mg
Mouse Anti-Lipoprotein Lipase [5D2]: Horseradish peroxidase (HRP)
Ask
View Details