hCAII-IN-7
Product Specifications
UNSPSC Description
hCAII-IN-7 (Compound R-13) is a potent human carbonic anhydrase (hCA) inhibitor with Kis of 60.7, 320.7, 2298, and 35.2 nM for hCA I, II, IV and IX, respectively[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaii-in-7.html
Solubility
10 mM in DMSO
Smiles
NS(=O)(C1=CC=C(C=C1)C(N2CCN(C[C@H]2CCO)CC3=CC=CC=C3)=O)=O
Molecular Weight
403.50
References & Citations
[1]Chiaramonte N, et al. 2-(2-Hydroxyethyl)piperazine derivatives as potent human carbonic anhydrase inhibitors: Synthesis, enzyme inhibition, computational studies and antiglaucoma activity. Eur J Med Chem. 2022;228:114026.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144268/hCAII-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144268/
Clinical Information
No Development Reported
Curated Selection
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