Trans-Cephalosporin

Trans substituted cephalosporin is an effective NDM-1 inhibitor, with an IC50 value of 0.13 μM.

Product Specifications

CAS Number

[2757462-75-0]

UNSPSC

12352005

Target

Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/trans-cephalosporin.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(CSC3=NC4=CC=CC=C4S3)CS[C@]2([H])[C@@H](OC)C1=O)O

Molecular Formula

C16H14N2O4S3

Molecular Weight

394.49

References & Citations

[1]Hu L, et al. Stereochemically altered cephalosporins as potent inhibitors of New Delhi metallo-β-lactamases. Eur J Med Chem. 2022 Feb 4;232:114174.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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