Trans-Cephalosporin
Trans substituted cephalosporin is an effective NDM-1 inhibitor, with an IC50 value of 0.13 μM.
Product Specifications
CAS Number
[2757462-75-0]
UNSPSC
12352005
Target
Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trans-cephalosporin.html
Solubility
10 mM in DMSO
Smiles
O=C(C(N12)=C(CSC3=NC4=CC=CC=C4S3)CS[C@]2([H])[C@@H](OC)C1=O)O
Molecular Formula
C16H14N2O4S3
Molecular Weight
394.49
References & Citations
[1]Hu L, et al. Stereochemically altered cephalosporins as potent inhibitors of New Delhi metallo-β-lactamases. Eur J Med Chem. 2022 Feb 4;232:114174.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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