SOS1-IN-9
Product Specifications
UNSPSC Description
SOS1-IN-9 is a potent SOS1 inhibitor with an IC50 of 116.5 nM for SOS1-KRAS G12C (WO2022028506A1, compound 302)[1].
Target Antigen
Ras
Type
Reference compound
Related Pathways
GPCR/G Protein;MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sos1-in-9.html
Solubility
10 mM in DMSO
Smiles
CC1=NC(N[C@@H](C2=CC(N)=CC(C(F)(F)F)=C2)C)=C3CN(CCC3=N1)C4CCOCC4
Molecular Weight
435.49
References & Citations
[1]Sos1 inhibitor, pharmaceutical composition containing same, and use therefor. WO2022028506A1.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144207/SOS1-IN-9-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144207/
Clinical Information
No Development Reported
CAS Number
2758900-76-2
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