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PRMT5-IN-18

PRMT5-IN-18 (Compound 002) is a potent PRMT5 inhibitor that can be used for the research of a disease mediated by PRMT5, such as cancer[1].

Product Specifications

CAS Number

2756849-68-8

UNSPSC

12352005

Target

Histone Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/prmt5-in-18.html

Solubility

10 mM in DMSO

Smiles

O=C1N(C[C@@H](O)[C@H]2NCC3=C(C=CC=C3)C2)CCN(CC)C4=CC(C(N(CC5)CCC65CC(OC)C6)=O)=CC=C14

Molecular Formula

C32H42N4O4

Molecular Weight

546.70

References & Citations

[1]Tetrahydroisoquinoline compounds and use thereof. WO2022002142A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PRMT5

Frequently Asked Questions

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