MAT2A-IN-6
MAT2A-IN-6 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally elevated in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-6 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-6 has the potential for the potential for the research of cancer diseases (extracted from patent WO2021254529A1, compound 18) [1].
Product Specifications
CAS Number
2756458-72-5
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mat2a-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(NC)C2=C(N(C3=CC=CC=C3Cl)C1=O)N=C(C(F)(F)F)C=C2)OC
Molecular Formula
C18H13ClF3N3O3
Molecular Weight
411.76
References & Citations
[1]Li Zhen, et al. Bicyclic compounds. Patent WO2021254529A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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