CDK7-IN-12
CDK7-IN-12 is a potent inhibitor of CDK7. CDK7-IN-12 plays a key role in transcriptional regulation and cell cycle regulation. CDK7-IN-12 effectively inhibit malignant tumor proliferation in vitro and in vivo. CDK7-IN-12 has the potential for the research of cancer disease (extracted from patent WO2021249417A1, compound 43) [1].
Product Specifications
CAS Number
2750638-94-7
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk7-in-12.html
Solubility
10 mM in DMSO
Smiles
FC(C1=C(C2=CNC3=C2C=CC=C3)N=C(N[C@@H]4CNCCC4)C5=NC=CN51)(F)F
Molecular Formula
C20H19F3N6
Molecular Weight
400.40
References & Citations
[1]Jing Wang, et al. Heterocyclic compounds and their derivatives. Patent WO2021249417A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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