DHODH-IN-19
DHODH-IN-19 is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-19 inhibits tumor growth. DHODH-IN-19 has the potential for the research of cancer and inflammation disease (extracted from patent WO2021238881A1, compound 1) [1].
Product Specifications
CAS Number
2742675-85-8
UNSPSC
12352005
Target
Dihydroorotate Dehydrogenase; DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dhodh-in-19.html
Solubility
10 mM in DMSO
Smiles
O=C1N(C2=CC(O[C@@H](C)C(F)(F)F)=C(C=C2F)/C(F)=C/C3=C(C=CC=C3F)Cl)N=C(N1CC)CO
Molecular Formula
C22H18ClF6N3O3
Molecular Weight
521.84
References & Citations
[1]Shuhui Chen, et al. Triazolones. Patent WO2021238881A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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