5-C-heptyl-DNJ
5-heptyl-DNJ is a potent GAA agonist with a Ki of 0.0047 μM. 5-C-heptyl-DNJ increases GAA activities by chaperrone effects[1].
Product Specifications
CAS Number
[2734265-63-3]
UNSPSC
12352005
Target
Glycosidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/5-c-heptyl-dnj.html
Solubility
10 mM in DMSO
Smiles
CCCCCCC[C@]1([C@H]([C@@H]([C@H](CN1)O)O)O)CO
Molecular Formula
C13H27NO4
Molecular Weight
261.36
References & Citations
[1]Atsushi Kato, et al. 5- C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease. J Med Chem. 2022 Feb 10;65 (3) :2329-2341.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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