HCV-IN-36

HCV-IN-36 (compound (S) -3h) is an orally active and potent HCV entry inhibitor. HCV-IN-36 shows excellent antiviral activity, with an EC50 of 0.016 μM and a CC50 (half-maximal cytotoxic concentration) of 8.78 μM[1].

Product Specifications

CAS Number

[2757963-81-6]

UNSPSC

12352005

Target

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/hcv-in-36.html

Solubility

10 mM in DMSO

Smiles

N#CC(C=CC(N(C)CCN(C)C)=C1)=C1CN(CC2)CCN2[C@@H](C3=CC=CC=C3)C4=CC=C(C=C4)Cl

Molecular Formula

C30H36ClN5

Molecular Weight

502.09

References & Citations

[1]Wang Y, Li J, Tan J, Yang B, Quan Y, Peng Z, Li Y, Li Z. Design, Synthesis, and Biological Evaluation of 2- ((4-Bisarylmethyl-piperazin-1-yl) methyl) benzonitrile Derivatives as HCV Entry Inhibitors. J Med Chem. 2022 Feb 10;65 (3) :2107-2121.