Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NSC405640

NSC405640 is a potent inhibitor of the MDM2-p53 interaction. NSC405640 rescues structural p53 mutations. NSC405640 selectively inhibits the growth of cell lines with wild-type p53[1].

Product Specifications

CAS Number

1135-99-5

UNSPSC

12352005

Hazard Statement

H301+H311+H331, H315, H319, H335, H400

Target

MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc405640.html

Purity

98.0

Solubility

10 mM in DMSO

Smiles

Cl[Sn](C1=CC=CC=C1)(C2=CC=CC=C2)Cl

Molecular Formula

C12H10Cl2Sn

Molecular Weight

343.82

Precautions

H301+H311+H331, H315, H319, H335, H400

References & Citations

[1]Chen S, et al. Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site. Cancer Cell. 2021;39 (2) :225-239.e8.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

KCNH7 (N-term) Rabbit Polyclonal Antibody
AP52306PU-N 400 µL

KCNH7 (N-term) Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
CINP Mouse Monoclonal Antibody [Clone ID: OTI4E9]
CF812210 100 µg

CINP Mouse Monoclonal Antibody [Clone ID: OTI4E9]

Sign In for Pricing
View Details
CD59 (NM_001127227) Human Over-expression Lysate
LC426726 20 µg

CD59 (NM_001127227) Human Over-expression Lysate

Sign In for Pricing
View Details
Human IgM Immunoglobulin (ICO-30), CF647 conjugate, 0.1mg/mL
BNC470364-100 1x 100 µL

Human IgM Immunoglobulin (ICO-30), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
ITGB6 Human Gene Knockout Kit (CRISPR)
KN417387 1 Kit

ITGB6 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
2-(2-Aminobenzoyl)pyridine
TRC-A593805-5G 5 g

2-(2-Aminobenzoyl)pyridine

Sign In for Pricing
View Details