EZH2-IN-11
EZH2-IN-11 is a potent inhibitor of E2HZ. The oncogenic activities of EZH2 have been shown by a number of studies in various different cancer types. EZH2-IN-11 has the potential for the research of cancer diseases (extracted from patent WO2019204490A1, compound 17) [1].
Product Specifications
CAS Number
2387402-80-2
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezh2-in-11.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Cl)=C(OC(C)(C2CCC(N3CC(OC)C3)CC2)O4)C4=C1C)NCC5=C(SC)C=C(C)NC5=O
Molecular Formula
C28H36ClN3O5S
Molecular Weight
562.12
References & Citations
[1]Alexandre Côté, et al. Modulators of methyl modifying enzymes, compositions and uses thereof. Patent WO2019204490A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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