HPK1-IN-25
HPK1-IN-25 (example 94) is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with a enzymatic activity IC50 of 129 nM. HPK1-IN-25 has the potential for cancer research[1].
Product Specifications
CAS Number
2403600-50-8
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-25.html
Solubility
10 mM in DMSO
Smiles
COC(C=C1)=CC=C1C2=CNC3=NC=C(C4=CN(C5CCN(CC5)C)N=C4)C=C32
Molecular Formula
C23H25N5O
Molecular Weight
387.48
References & Citations
[1]Jing Li, et al. Pyrrolo [2, 3-b] pyridines or pyrrolo [2, 3-b] pyrazines as hpk1 inhibitor and the use thereof. WO2019238067A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
Frequently Asked Questions
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