MRS4620
MRS4620 is a potent CD73 inhibitor, with a Ki of 0.436 nM. MRS4620 can be use for the research of cancer immunoresearch[1].
Product Specifications
CAS Number
2411665-73-9
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mrs4620.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@](N2C(N(/C(C=C2)=N\OCC3=CC=C(C=C3)I)C)=O)([H])O[C@@H]([C@H]1O)COP(CP(O)(O)=O)(O)=O
Molecular Formula
C18H24IN3O11P2
Molecular Weight
647.25
References & Citations
[1]Scortichini M, et, al. Structure-Activity Relationship of 3-Methylcytidine-5'-α, β-methylenediphosphates as CD73 Inhibitors. J Med Chem. 2022 Feb 10;65 (3) :2409-2433.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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