MurB-IN-1
Product Specifications
UNSPSC Description
MurB-IN-1 (compound 44) is an inhibitor of uridine diphosphate-N-acetylenolpyruvylglucosamine reductase (MurB), with a Kd 3.57 μM. MurB, a target in P. aeruginosa, is an opportunistic infectious agent causing death[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/murb-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(Cl)=C(C=C1N2N=CC(C(O)=O)=C2C(F)(F)F)Cl
Molecular Weight
339.10
References & Citations
[1]Acebrón-García-de-Eulate M, et, al. Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J Med Chem. 2022 Feb 10;65(3):2149-2173.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-144071/MurB-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-144071/
Clinical Information
No Development Reported
CAS Number
2883232-46-8
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