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AKT-IN-9

AKT-IN-9 is a potent inhibitor of AKT. Protein kinase B (PKB, also known as AKT) is central to PI3K/AKT/mTOR signaling in cells, and its function is important for cell growth, survival, differentiation and metabolism. AKT-IN-9 has the potential for the research of breast and prostate cancer (extracted from patent WO2021185238A1, compound 1) [1].

Product Specifications

CAS Number

[2709045-53-2]

UNSPSC

12352005

Target

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/akt-in-9.html

Solubility

10 mM in DMSO

Smiles

CC(C)NC[C@H](C1=CC=C(C=C1)Cl)C(N2C3CN(C4=C5C(NC=C5)=NC=N4)CC2CC3)=O

Molecular Formula

C24H29ClN6O

Molecular Weight

452.98

References & Citations

[1]Xin Li, et al. Thickened dicyclic derivatives, their preparation methods and their application in medicine. Patent WO2021185238A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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